The genetic counselor called me today to further discuss the fetal DNA results from my miscarriage in February.
She confirmed that the fetus WAS a carrier of Fragile X, but that the real problem was Trisomy 9. Then she went on to give me a few interesting tidbits:
1. Trisomy 9 is the cause of 50% of first trimester miscarriages. (This conflicts with what Dr. Google says about it being “rare”.)
2. Trisomy 9 is completely random; it doesn’t indicate future T9 pregnancies.
3. Trisomy 9 is never compatible with life.
4. Trisomy 9 can be screened out with PGD.
Regarding Tidbit #4, the genetic counselor also mentioned that the hospital has changed its protocol for PGD. Instead of doing Day 3 biopsy and getting the results in time for a Day 5 transfer, they’re now doing Day 5 biopsies and only FET’s. There is some data to suggest that removing a few cells from a Day 5 blastocyst screws ’em up less than taking them from a Day 3 embryo. (But I heard the opposite from the Genesis Genetics lab. Honestly, sometimes I think it’s all bullsh*t.)
So, if we change our minds and decide to do PGD with our next IVF after all, at least we’ll be spared the stress of going to the hospital on Day 5 without knowing if there are any embies to put in. And I’ll be spared the sudden Crinone/Estrace withdrawal I experienced on all four of my IVF cycles! Somehow that makes me feel a little better. ❤